Haplogroup R0 (mtDNA)

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Haplogroup R0
Possible time of origin	23,600 to 54,900 YBP[1]
Possible place of origin	Near East or South Asia
Ancestor	R
Descendants	HV, R0a
Defining mutations	73, 11719[2]

In human mitochondrial genetics,Haplogroup R0 (formerly known asHaplogroup pre-HV^[3]) is amitochondrial DNA (mtDNA) haplogroup.

Contents

   

• 1 Origin
• 2 Distribution
• 3 Subclades
  • 3.1 Tree
• 4 See also
• 5 References
• 6 External links

Origin

Haplogroup R0 derives from the macro-haplogroup R. It is an ancestral haplogroup to R0a and Haplogroup HV (and therefore to Haplogroup H and Haplogroup V).

Distribution

Haplogroup R0 occurs frequently in the Arabian Plate with its highest frequency in Socotri(Population 50,000 Yemen) 38% ^[4] and it is also found in a high frequency in the Kalash(Population 6,000 in Pakistan) with 23%^[5] smaller frequency in North Africa, the Horn of Africa, Anatolia, Iranian Plateau & Dalmatia. Its greater variety in the Arabian Plate suggests R0a originated in and spread from there.

Subclades

Tree

This phylogenetic tree of haplogroup R0 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation^[2] and subsequent published research.

• R
  • R0 or pre-HV
    • R0a or (preHV)1
      • R0a1 or (preHV)1a
        • R0a1a
      • 60.1T
        • R0a2 or (preHV)1b
          • R0a2a
          • R0a2b
          • R0a2c
          • R0a2d
          • R0a2e
      • HV
        • HV0
        • HV1
        • 73
        • HV4
        • HV5
        • H

See also

• Genealogical DNA test
• Genetic Genealogy
• Human mitochondrial genetics
• Population Genetics

Evolutionary tree of human mitochondrial DNA (mtDNA) haplogroups

Mitochondrial Eve (L)

L0

L1–6

L1

L2

L3

L4

L5

L6

M

N

CZ

D

E

G

Q

A

S

R

I

W

X

Y

C

Z

B

F

R0

pre-JT

P

U

HV

JT

K

H

V

J

T

References

1. Jump up^ Soares, P; Ermini, L; Thomson, N; Mormina, M; Rito, T; Röhl, A; Salas, A; Oppenheimer, S et al. (2009). "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". American Journal of Human Genetics 84 (6): 740–59.doi:10.1016/j.ajhg.2009.05.001. PMC 2694979. PMID 19500773.
2. ^ Jump up to:^a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386–E394.doi:10.1002/humu.20921. PMID 18853457. Retrieved 2009-05-20.
3. Jump up^ Haplogroup H Sub-clades, Family Tree DNA
4. Jump up^ Viktor Cerny et al. 2008, Out of Arabia—The Settlement of Island Soqotra as Revealed by Mitochondrial and Y Chromosome Genetic Diversity.
5. Jump up^ Quintana-Murci, Lluís et al. (2004). "Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor.". American Journal of Human Genetics 74: 2004. doi:10.1086/383236. PMC 1181978. PMID 15077202.

External links

• General
  • Ian Logan's Mitochondrial DNA Site
  • Mannis van Oven's PhyloTree
• Haplogroup R0
• Spread of Haplogroup pre-HV, from National Geographic